Comparative evaluation of therapeutic efficacy of Jambu (Syzygium cumini (L.) Skeels.) and Musta (Cyperus rotundus L. subsp.) in management of Medoroga - An open randomized controlled clinical trial
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Expected difference of BMI of 0.5kg/m2 will be considered significant.
研究概览
简要总结
In this era of modernization, Obesity is a curse to the human beings. In spite of advancement in treatment of Obesity, its prevalence is increasing significantly and is considered an emergency health problem all over the World.
It is an epidemic in the world population and has been designated as a research priority by the leading global health organizations. It is a primary causal factor in many diseases, including type 2 Diabetes, Hypertension, Cardiovascular disease, Dyslipidaemia, Stroke, and Liver disease.
The drug Jambu is selected in Medoroga for the present study as it is nontoxic, cost effective, can be administered orally, it has Sita Virya, Katu Vipaka, Kashaya, Tikta Rasas and Kapha ,Medohara property mentioned in Shushruta Samhita Adhyaya 38 Dravyasangrahaniya Adhyaya Shloka 48 of Nyagrodhadi Gana and many research activities experimentally proved the Hypolipidemic activity in modern science. Hence selected for clinical study with standard control drug Musta (RM Kalpana IJAPR-2014.2(3):355-363).
The medication modalities in Ayurveda followed with inclusive utilization have an enormous impact in managing lifestyle disorders and that most of these disorders are preventable and many are even reversible. One key advantage of Ayurveda over Allopathy is that the herbs uses have minimal side effects, Allopathic medicines are synthesized in laboratories and have side effects ranging from mild to severe. Ayurveda provides a holistic healing approach that removes the problem from the root rather than just targeting symptoms. Ayurveda not only have potential to treat diseases but helpful to eradicate it completely which does not revert it and also help full to prevent one from causing diseases condition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients having BMI more than 30.
排除标准
- •Patients below 30 years, and above 50 years.
- •Patients having severe Cardiac anomalies.
- •Pregnant and lactating women.
- •Obesity produced due to certain secondary causes.
- •Drug induced Obesity.
- •Hereditary indisposition.
- •Patient suffering from any other grave disease also excluded.
- •Endocrinal origin Obesity excluded.
- •Diabetic patient excluded.
- •Patient doing exercise will be excluded.
结局指标
主要结局
Expected difference of BMI of 0.5kg/m2 will be considered significant.
时间窗: 90 days
次要结局
- Weight reduction.(180 days.)
研究者
Jyoti Jagtap
D Y Patil University, School of Ayurveda Nerul, Navi Mumbai
