ISRCTN53060944已完成不适用
Evaluation of the mucosa-permeability of the stomach measured by the Ussing Chambers technique in patients with functional dyspepsia before and after treatment with amitriptyline
Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)0 个研究点目标入组 60 人开始时间: 2006年6月7日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age 18-65 years
- •2. Patients have to take part in the amitriptyline study (ISRCTN76116512)
- •3. Functional dyspepsia (Nepean dyspepsia index [NDI] >25)
- •4. No depression (Zung self-rating depression scale <50)
- •5. No effect on proton pump inhibitor (PPI), or a constant three-month dosage of PPI
- •6. No medications which will influence the intestine
排除标准
- •1. Gastroduodenal surgery in history
- •2. Reflux-like dyspepsia (Rome II criteria)
- •3. Use of antidepressants
- •4. Organic abnormalities
- •5. Severe cardiac, renal, pulmonary, hepatic, or systemic diseases, hyperthyroidism, glaucoma and epilepsy
研究者
相似试验
已完成
不适用
Evaluation of the mucosa-permeability of the stomach measured by the Ussing Chambers technique in patients with functional dyspepsia before and after treatment with amitriptyline.Functional dyspepsia.NL-OMON20933Academic Medical Center (AMC) Amsterdam, department of gastroenterology60
尚未招募
不适用
In vivo evaluation of esophageal mucosal permeability in patients with non erosive reflux diseaseGastro-esophageal reflux disease (GERD)heartburn10017977NL-OMON32964Academisch Medisch Centrum50
已完成
不适用
The evaluation of intestinal permeability for damage of mucosal injury from NSAIDSVolunteerJPRN-UMIN000003258Aichi Medical University10
已完成
不适用
An analysis of permeability of the gastrointestinal epithelium in functional dyspepsia (FD) patientsFunctional dyspepsiaJPRN-UMIN000023397kyushu university58
已完成
不适用
Assessment of epithelial permeability in asthma through nuclear imagingRespiratoryAsthmaISRCTN86496888Southampton University Hospitals NHS Trust (UK)40