NL-OMON32964
Not yet recruiting
Not Applicable
In vivo evaluation of esophageal mucosal permeability in patients with non erosive reflux disease - permeability and NERD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gastro-esophageal reflux disease (GERD)
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 50
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Age 18 \* 75 years
- •\- Written informed consent
- •Healthy volunteers:
- •\- Age 18 \* 75 years
- •\- Written informed consent
Exclusion Criteria
- •\- Surgery of the GE\-tract other than appendectomy
- •\- Use of PPI, or other medication influencing gastric or GI motility
- •\- patients unable to undergo endoscopy
- •\- Allergy to fluoresceine, midazolam, buscopan
- •\- Renal insuffiency
- •Healthy volunteers:
- •\- Surgery of the GE\-tract other than appendectomy
- •\- Gastro\-intestinal complaints, including typical GERD complaints
- •\- Medication influencing gastric motility or GI motility
- •\- Allergy to fluoresceine, midazolam, buscopan
Outcomes
Primary Outcomes
Not specified
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