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Clinical Trials/NL-OMON32964
NL-OMON32964
Not yet recruiting
Not Applicable

In vivo evaluation of esophageal mucosal permeability in patients with non erosive reflux disease - permeability and NERD

Academisch Medisch Centrum0 sites50 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gastro-esophageal reflux disease (GERD)
Sponsor
Academisch Medisch Centrum
Enrollment
50
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • \- Age 18 \* 75 years
  • \- Written informed consent
  • Healthy volunteers:
  • \- Age 18 \* 75 years
  • \- Written informed consent

Exclusion Criteria

  • \- Surgery of the GE\-tract other than appendectomy
  • \- Use of PPI, or other medication influencing gastric or GI motility
  • \- patients unable to undergo endoscopy
  • \- Allergy to fluoresceine, midazolam, buscopan
  • \- Renal insuffiency
  • Healthy volunteers:
  • \- Surgery of the GE\-tract other than appendectomy
  • \- Gastro\-intestinal complaints, including typical GERD complaints
  • \- Medication influencing gastric motility or GI motility
  • \- Allergy to fluoresceine, midazolam, buscopan

Outcomes

Primary Outcomes

Not specified

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