Reduction or Extension of COnduction Time With Ventricular Electromechanical Remodeling (RECOVER)

• Conditions: Heart Failure
• Interventions: Diagnostic Test: Device interrogation

• Registration Number: NCT04397224
• Lead Sponsor: Samsung Medical Center

Brief Summary

This prospective multicenter registry study aims to detect the serial changes in ventriculo-ventricular conduction times according to cardiac-resynchronization therapy response.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-07-20
• Study First Submitted: 2020-05-17
• Study First Submitted QC: 2020-05-17
• Study First Posted: 2020-05-21
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-29
• Last Update Posted: 2021-06-30
• Primary Completion: 2022-07-20
• Study Completion: 2024-07-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• meeting the current ESC or ACCF/AHA/HRS Class I or Class IIa indications for cardiac-resynchronization (CRT) implant

Exclusion Criteria

• Myocardial infarction, unstable angina within 40 days prior the enrollment
• Recent cardiac revascularization in the 4 weeks prior to the enrollment or planned for the 3 months following
• Cerebrovascular accident (CVA) or transient ischemic attack (TIA) in the 3 months prior to the enrollment
• Primary valvular disease requiring surgical correction
• Pregnant or are planning during the duration of the investigation
• Status 1 candidate for cardiac transplantation or consideration for transplantation over the next 12 months
• Post-cardiac transplantation
• Life expectancy < 12 months
• Currently participating in any other clinical investigation except for observational registry

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CRT non-responder	Device interrogation	-
CRT responder	Device interrogation	-

Primary Outcome Measures

Name	Time	Method
Serial change of ventriculo-ventricular conduction times	from enrollment to last follow-up (2 years)	Reduction or extension of ventriculo-ventricular conduction times

Trial Locations

Locations (6)

Sejong General Hospital; 🇰🇷 Bucheon, Korea, Republic of

Samsung Medical Center; 🇰🇷 Seoul, Korea, Republic of

Seoul National University Bundang Hospital; 🇰🇷 Seongnam, Korea, Republic of

Chungnam National University Hospital; 🇰🇷 Daejeon, Korea, Republic of

Eulji University Hospital; 🇰🇷 Daejeon, Korea, Republic of

Samsung Changwon Medical Center; 🇰🇷 Changwon, Korea, Republic of