A Single-center Observational Study to Examine the Occurrence of Ventricular Arrhythmias After Pulmonary Vein Isolation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Ventricular Arrhythmias
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
- Enrollment
- 111
- Locations
- 1
- Primary Endpoint
- Ventricular arrhythmias
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.
Detailed Description
Atrial fibrillation is the most common arrhythmia with a lifetime risk for development of over 20%. Pulmonary vein isolation is now established as therapy of choice for patients with symptomatic atrial fibrillation. It is well known that this interventional therapy inevitably modulates the intracardiac autonomic nervous system. While this ablation might alter atrial electrophysiology beneficially, the impact on ventricular electrophysiology remains unclear.
Investigators
Prof. Dr. Christian Meyer
Prof. Dr.
Universitätsklinikum Hamburg-Eppendorf
Eligibility Criteria
Inclusion Criteria
- •Age \> 18 years
- •Paroxysmal atrial fibrillation scheduled to undergo pulmonary vein isolation
Exclusion Criteria
- •Age \< 18 years
- •Persistent atrial fibrillation
- •Life expectancy less than 12 months
- •Acute myocardial infarction, coronary artery bypass graft surgery, open heart surgery, or percutaneous transluminal coronary angioplasty within less than 3 months prior to inclusion
- •Documentation of \>30 premature ventricular complexes per hour, salvos or ventricular tachycardias prior to atrial fibrillation ablation
Outcomes
Primary Outcomes
Ventricular arrhythmias
Time Frame: one year
Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.
Secondary Outcomes
- Arrhythmia recurrence(one year)