A study for the effects of ingestion of collagen octapeptide (Gly-Ala-Hyp-Gly-Leu-Hyp-Gly-Pro) on endothelial function in healthy adult with lower endothelial function.
- Conditions
- one
- Registration Number
- JPRN-UMIN000031071
- Lead Sponsor
- TTC Co.,Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
(1) Subjects who take pharmaceutical agent, functional food, or supplement that may affect the study. (2) Subjects who routinely use food rich in collagen. (3) Ineligible subjects with abnormal laboratory value or cardiopulmonary function. (4) Subjects having possibilities for emerging allergy related to the study. (5) Subjects who are under medication. (6) Subjects who are under treatment or have a history of serious disease (e.g., diabetes, liver disease, kidney disease, or heart disease). (7) Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination. (8) Subjects who have habits affecting research results, such as doing shift work day and night, or Subjects who have a plan that affect research results such as day and night shift work and overseas. (9) Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study. (10) Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating. (11) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire. (12) Subjects who cannot obey the restriction item (prohibited matter) during the study. (13) Subjects who are hypertension stage I (SBP>=140 mmHg and/or DBP>=90 mmHg). (14) Subjects who have baPWV value 1400 cm/s or more. (15) Subjects judged as unsuitable for the study by the investigator for other reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Flow Mediated Dilation (FMD)
- Secondary Outcome Measures
Name Time Method Fatigue sensation (VAS) Athens Insomnia Scale Pittsburgh Sleep Quality Index