THE IMPACT OF EARLY PERCUTANEOUS TRACHEOSTOMY ON REDUCTION OF THE INCIDENCE OF VENTILATOR ASSOCIATED PNEUMONIA AND THE COURSE AND OUTCOME OF ICU PATIENTS
Not Applicable
- Conditions
- Other postprocedural respiratory disordersJ95.8A41.9Sepsis, unspecified
- Registration Number
- DRKS00009905
- Lead Sponsor
- Sveucilišna klinicka bolnica MostarSpecialist of anesthesiology and reanimatology. Head of Department of anesthesiology, reanimatology and intensive care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
The basic criterion for the inclusion in the research was the expected duration of mechanical ventilation for at least 14 days based on the diagnosis of patients sequential organ failure assessment (SOFA) score >5, acute physiology and chronic health evaluation (APACHE II) scores >10, arterial oxygen partial pressure (PaO2) =60 mmHg with fraction of inspired oxygen (FiO2) 0.5 and positive end expiratory pressure (PEEP) of at least 8 cm H2O.
Exclusion Criteria
Patients under 18 years
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is number of patients with aquired pneumonia that are mechanically ventilated who are going to be diagnosed based on clinical criteria (CRP value, microbiological analysis of material taken during brochoscopy, Chest x-ray, body temperature)
- Secondary Outcome Measures
Name Time Method Septic episodes were diagnosed based on: clinical symptoms, laboratory results, hemodynamic parameters and microbiological analysis in accordance with the usual clinical practice, as well as on the established criteria for the diagnosis of sepsis: temperature >38 °C or <36 °C, heart rate >90 beats per minute, respiratory rate >20 breaths per minute, abnormal white blood cell count >12,000/mm3 or <4,000/ mm3 or >10% bands, occurrence of hypoperfusion, hypotension and oliguria (12).