Are there differences in the clinical course of critically ill patients undergoing prolonged mechanical ventilation when performing tracheostomy early or late?

Completed

• Conditions: Critically ill patients with respiratory failure of different etiologies and prolonged mechanical ventilation requirements; Respiratory

• Registration Number: ISRCTN22208087
• Lead Sponsor: niversity Hospital of Bellvitge (Hospital Universitari de Bellvitge) (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1452

Inclusion Criteria

Patients admitted to the intensive care unit (ICU) with:
1. Aged over 17
2. Over 2 days of mechanical ventilation and expected by attending physician to be 7 or more days of mechanical ventilation

Exclusion Criteria

1. Patients already tracheotomized
2. Patients previously included in another trial
3. Technical difficulty to perform a percutaneous tracheotomy
4. Patients without limitation of life support but any of the following conditions: intracranial hypertension (ICP> 15), risk of bleeding (platelets <50000 or prothrombin time INR> 1.5), severe respiratory failure (PEEP> 10cmH20 or PO2 / FiO2 <100)
5. Patients with poor prognosis and any type of decision to limit life support measures
6. Patients requiring urgent tracheotomy on medical grounds (to improve the management of the upper airway, neurological illness, etc.)

Study & Design

• Study Type: Interventional
• Study Design: Not specified