Effect of Triphaladi kwatha and Aragawadhadikwatha in hyperacidity.

Phase 4

Not yet recruiting

• Conditions: Gastro-esophageal reflux disease without esophagitis. Ayurveda Condition: AMLAPITTAM,

• Registration Number: CTRI/2023/09/057257
• Lead Sponsor: Dr Lubna Sadaf Khan

Brief Summary

Due to changing life style, dietary inconsistency, mental stress, aerated drinks, preserved food, spicy foods, suburbanization Amlapitta has become a common problem which affects day to day life. In contemporary science they included Amlapitta as symptoms of disease but in Ayurvedic classic they mentioned it as a separate disease. In modern science there is no adequate treatment available but in Ayurvedic classic various Samhitas mentioned effective management, hence there is a need of drug which will digest or metabolize the Saama Pitta and prevent the Agnimandya to break the Samprapti of Amlapitta.

Signs and symptoms of Amlapitta mentioned in the Ayurvedic texts are very similar to hyper acidity. The stomach normally secretes acid that is essential in the digestive process. The acid helps in the breakdown of food during digestion. When there is excess production of the acid

by gastric gland of the stomach, it results in the condition known as acidity.

This is an attempt to introduce Ayurveda based medicine in Amlapitta so here selected study on Amlapitta with Triphaladi Kwatha and Aragwadhamrutadi Kwatha.

Triphaladi Kwatha is mentioned in Gadnigraha9. The ingredients present in the formulation are Haritaki, Bibhitaki, Amalaki, Patolpatra, kutaki, 10. The most of the Dravya have Laghu, Ruksha Guna’s and Katu, Tikta, Kashaya Rasa, which acts against the excessive Drava and Tikshna Guna’s of Pitta, on the other hand they all play specific role in management of Mandagni.

Aragwadhamrutadi Kwatha is mention in Sahastrayoga11 which is a unique herbal combination of Aragwadha, Amruta, Haritaki, Khadira 12.

These drugs are useful in Amlapitta which are easily available, cost effective and show better palatability. Ample number of patients are available in day-to-day practice hence, selected this topic for study.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-10-26
• Study Start: 2023-11-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 66

Inclusion Criteria

• Age limit is from 18 to 60 years irrespective of Gender, Occupation, Religion and Economical condition.
• 2. Patients with the following symptoms of Urdhwaga Amlapitta for more than 1-2 month will be included according to Madhav Nidana (51/4-6)14 namely, The symptoms of Amlapitta are as, 1.
• Chhardi (Vomiting) 2.
• Tikta-Amla-Udgara (Belching- Bitter/ Sour) 3.
• Shirashoola (Headache) 4.
• Utklesha/ Hrullas (Nausea) 5.
• Hruddaha (Burning in chest).

Exclusion Criteria

• 1. Pregnant and Lactating women.
• 2. Patients with severe Vomiting and Diarrhoea and those who cannot take medicine orally.
• 3. Amlapitta along with other chronic disease and its associated complications.
• 4. Known case of Diabetes Mellitus.
• 5. Patients with gastric ulcers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Triphaladi Kwatha and Aragwadhamrutadi Kwatha in Urdhwaga Amlapitta	0th day 15th day 30th day

Secondary Outcome Measures

Name	Time	Method
To observe the adverse effects of Triphaladi Kwatha and Aragwadhamrutadi Kwatha	0th day 15th day 30th day

Trial Locations

Locations (1)

Sane Guruji Arogya Kendra; 🇮🇳 Pune, MAHARASHTRA, India

Sane Guruji Arogya Kendra

🇮🇳Pune, MAHARASHTRA, India

Dr Lubna Sadaf Khan

Principal investigator

9766247689

lubnaskhan30@gmail.com