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临床试验/CTRI/2023/09/057257
CTRI/2023/09/057257尚未招募4 期

A comparative clinical study to evaluate the efficacy of Triphaladi Kwatha and Aragwadhamrutadi Kwatha in the management of Urdhwaga Amlapitta.

Dr Lubna Sadaf Khan1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2023年11月9日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
66
试验地点
1
主要终点
To compare the efficacy of Triphaladi Kwatha and Aragwadhamrutadi Kwatha in Urdhwaga Amlapitta

研究概览

简要总结

Due to changing life style, dietary inconsistency, mental stress, aerated drinks, preserved food, spicy foods, suburbanization Amlapitta has become a common problem which affects day to day life. In contemporary science they included Amlapitta as symptoms of disease but in Ayurvedic classic they mentioned it as a separate disease. In modern science there is no adequate treatment available but in Ayurvedic classic various Samhitas mentioned effective management, hence there is a need of drug which will digest or metabolize the Saama Pitta and prevent the Agnimandya to break the Samprapti of Amlapitta.

Signs and symptoms of Amlapitta mentioned in the Ayurvedic texts are very similar to hyper acidity. The stomach normally secretes acid that is essential in the digestive process. The acid helps in the breakdown of food during digestion. When there is excess production of the acid

by gastric gland of the stomach, it results in the condition known as acidity.

This is an attempt to introduce Ayurveda based medicine in Amlapitta so here selected study on Amlapitta with Triphaladi Kwatha and Aragwadhamrutadi Kwatha.

Triphaladi Kwatha is mentioned in Gadnigraha9. The ingredients present in the formulation are Haritaki, Bibhitaki, Amalaki, Patolpatra, kutaki, 10. The most of the Dravya have Laghu, Ruksha Guna’s and Katu, Tikta, Kashaya Rasa, which acts against the excessive Drava and Tikshna Guna’s of Pitta, on the other hand they all play specific role in management of Mandagni.

Aragwadhamrutadi Kwatha is mention in Sahastrayoga11 which is a unique herbal combination of Aragwadha, Amruta, Haritaki, Khadira 12.

These drugs are useful in Amlapitta which are easily available, cost effective and show better palatability. Ample number of patients are available in day-to-day practice hence, selected this topic for study.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)

入选标准

  • Age limit is from 18 to 60 years irrespective of Gender, Occupation, Religion and Economical condition.
  • Patients with the following symptoms of Urdhwaga Amlapitta for more than 1-2 month will be included according to Madhav Nidana (51/4-6)14 namely, The symptoms of Amlapitta are as,
  • Chhardi (Vomiting)
  • Tikta-Amla-Udgara (Belching- Bitter/ Sour)
  • Shirashoola (Headache)
  • Utklesha/ Hrullas (Nausea)
  • Hruddaha (Burning in chest).

排除标准

  • Pregnant and Lactating women.
  • Patients with severe Vomiting and Diarrhoea and those who cannot take medicine orally.
  • Amlapitta along with other chronic disease and its associated complications.
  • Known case of Diabetes Mellitus.
  • Patients with gastric ulcers.

结局指标

主要结局

To compare the efficacy of Triphaladi Kwatha and Aragwadhamrutadi Kwatha in Urdhwaga Amlapitta

时间窗: 0th day 15th day 30th day

次要结局

  • To observe the adverse effects of Triphaladi Kwatha and Aragwadhamrutadi Kwatha(0th day 15th day 30th day)

研究者

发起方
Dr Lubna Sadaf Khan
申办方类型
Other [self]

研究点 (1)

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