Impact of supervised diet and lifestyle modifications on weight loss, body fat distribution and insulin resistance in adult Indian obese patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- • To study the impact of supervised dietary changes and lifestyle modifications on weight loss (in kgs over 3 months) in obese Indian adults.
研究概览
简要总结
This study is an interventional trial to evaluate the impact of
diet and lifestyle modifications on weight, insulin resistance
and fat distribution of adult Indian obese patients. On initial
evaluation, a detailed history was taken and the following
parameters were noted-
• BMI in kg/m2
• Waist circumference in centimeters
• OGTT in mg/dl
• Fasting insulin levels
• Fat distribution- subcutaneous, visceral and total at L4-
L5 disc level using a single cut section CT scan.
The patients are given dietary consultation by an expert
dietician and followed up regularly. They are also taught
yoga in our hospital for 1 week under the department of
physiology by a trained yoga teacher and then asked to
continue practising at home. These patients are followed up
for 3 months and the above parameters are again noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with obesity, defined as Body Mass Index > 30.
排除标准
- •1.Patients < 18 years and >60years.
- •2.Patients with known hypothalamic-pituitary & genetic causes of obesity 3.Patients who refuse consent for the study 4.Patients, who are on medications that can affect weight such as thyroxine, steroids.
- •5.Patients who do not fit into our CT machine.
结局指标
主要结局
• To study the impact of supervised dietary changes and lifestyle modifications on weight loss (in kgs over 3 months) in obese Indian adults.
时间窗: 3 months
• To study the body fat distribution ( by single cut section of abdomen at L4-L5 disc level) and insulin resistance ( by HOMA IR) in adult Indian obese patients.
时间窗: 3 months
• To study the effect of weight loss on insulin resistance and body fat distribution in adult Indian obese patients
时间窗: 3 months
次要结局
未报告次要终点