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Clinical Trials/NCT05650489
NCT05650489
Completed
N/A

Autistic Features in Relation to Motor Function and Quality of Life in Children With an Autism Spectrum Disorder

Cairo University1 site in 1 country40 target enrollmentApril 15, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism Spectrum Disorder
Sponsor
Cairo University
Enrollment
40
Locations
1
Primary Endpoint
Motor Development
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Although motor limitations are not currently considered a as clinical manifestation of autism spectrum disorder, should not be ignored due to their high incidence and considerable influence on life quality functional activity

Registry
clinicaltrials.gov
Start Date
April 15, 2020
End Date
March 20, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amira Mahmoud Abd-elmonem

Assist Prof. Physiacl therapy for pediatric department, faculty of physical therapy , Cairo university

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Both sex,
  • age ranges from 3 to 5 years,
  • mild to moderate autistic features according to childhood autism rating scale ,
  • were able to sit alone independently

Exclusion Criteria

  • Significant visual or auditory defects,
  • history of cerebral palsy or psychiatric disorder (e.g attention deficit hyperactivity disorder)

Outcomes

Primary Outcomes

Motor Development

Time Frame: baseline assessment

The Peabody Developmental Motor Scales-Second Edition: The gross motor function domain will be assessed in the current study. The gross motor function domains contain four subtests. Reflexes, Stationary ,Locomotion and Object Manipulation . Grading and Scoring of the PDMS-2 The therapist will ask the child to do a specific item and observes how the child is doing the task. Items are scored as 2, 1 or 0. 0 = child cannot or will not attempt an item or the attempt does not indicate that the specific skill is emerging * child's performance shows a clear resemblance to item mastery criteria but does not fully meet the criteria or there are signs of an emerging skill * child performs item according to the criteria specified for mastering the skill

Autism Index

Time Frame: baseline assessment

Gilliam autism rating scale: Items on the developmental subscale address behaviors and milestones in the first 36 months of life. Items on the first three behavioral subscales are rated on a four point like scale ranging from Never Observed (0) to Frequently Observed (3). After completing it, the examiner calculated the total raw scores then converted into scaled scores and percentile ranks according to the examiner's manual. Higher scaled scores on a subscale represent severe autistic behavior. Finally, the total scaled scores were calculated to measure the autism index according to the examiner's manual. The higher the autism index, the higher the probability the individual has autism and the more severe the autistic behavior

Pediatric Quality of life Inventory Scale

Time Frame: baseline assessment

Pediatric Quality of life Inventory Scale: The Arabic version will be used to assess quality of life. It contains questions about child's physical, emotional, social, and school functioning in the past 7 days. Parents/ child self-administered the quality of life after introductory instructions from the administrator. On the quality of life Generic Core Scales, for ease of interpretability, items are 22 reversed scored and linearly transformed to a 0-100 scale, so that higher scores indicate better Health-Related quality of Life. To reverse score, transform the 0-4 scale items to 0-100 as follows: 0-100, 1=75, 2= 50, 3= 25 and 4= 0. Finally, the Scale Score for each dimension and Total Scale Score were calculated

Study Sites (1)

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