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临床试验/CTRI/2026/02/103946
CTRI/2026/02/103946尚未招募不适用

COMPARISION OF EFFICACY OF POST OPERATIVE ANALGESIA BY ULTRASOUND GUIDED BILATERAL ERECTOR SPINAE BLOCK USING 0.25 % LEVOPBUPIVACAINE WITH AND WITHOUT DEXMEDETOMIDINE IN ELECTIVE ADULT CARDIAC SURGERIES- RANDOMIZED DOUBLE BLINDED STUDY

SHAIK NISA SHAFAQH1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2026年3月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1

研究概览

简要总结

Postoperative pain following cardiac surgery is multifactorial, arising from sternotomy, tissue trauma, drains, and thoracic cage retraction. Adequate analgesia is essential for enhanced recovery, early mobilization, and reduction of opioid consumption. The erector spinae plane (ESP) block has emerged as a safe and effective regional analgesic technique in cardiac surgical patients. Dexmedetomidine, when used as an adjuvant to local anesthetics, may prolong analgesic duration and improve pain control.

This prospective, randomized, double-blinded study aims to compare the analgesic efficacy of ultrasound-guided bilateral ESP block using 0.25% levobupivacaine with and without dexmedetomidine in adult patients undergoing elective cardiac surgery.

Fifty patients will be randomized into two groups. Group LP will receive bilateral ESP block with 0.25% levobupivacaine, while Group LD will receive 0.25% levobupivacaine with dexmedetomidine (20 µg).

The primary outcomes include total opioid consumption and time to first rescue analgesia within 24 hours postoperatively. Secondary outcomes include postoperative pain scores (VAS), haemodynamic parameters, sedation scores, duration of mechanical ventilation, ICU stay, and adverse effects.

The study is designed to evaluate whether dexmedetomidine provides superior postoperative analgesia when used as an adjuvant in ESP block for cardiac surgical patients.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients undergoing elective cardiac surgeries requiring general anaesthesia Ejection fraction more than 40 percent.

排除标准

  • Refusal of patient, age lessthan 18 years, inflammatory or infection at injection site, allergy to local anaesthetics, altered coagulation profile, spine deformities.

研究者

发起方
SHAIK NISA SHAFAQH
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

SHAIK NISA SHAFAQH

Assistant professor

研究点 (1)

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