Comparison Of Postoperative Analgesic Efficacy Of 0.5 Percentage Ropivacaine With Dexmedetomidine Versus 0.5 Percentage Ropivacaine With Nalbuphine In Ultrasound Guided Erector Spinae Plane Block For Breast Augmentation Surgeries A Prospective Randomized Double Blinded Study
Overview
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Mohammed Asjad T
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in minutes or hours within 24 hours post surgery.
Overview
Brief Summary
This prospective, randomized, double blind study was conducted to compare the postoperative analgesic efficacy of two drug combinations in ultrasound guided erector spinae plane ESP block for patients undergoing breast augmentation surgery. One group received 0.5 Percentage ropivacaine with dexmedetomidine, while the other received 0.5 Percentage ropivacaine with nalbuphine.
The study assessed parameters such as
Duration and quality of postoperative analgesia
Total rescue analgesic requirement
Hemodynamic stability and side effects
The results indicated which adjuvant dexmedetomidine or nalbuphine when combined with ropivacaine, provided superior and longer-lasting pain relief with minimal adverse effects.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
Inclusion Criteria
- •Patients under ASA Physical Status I and II undergoing breast augmentation surgery Plastic Surgery.
- •Gender Transgender patients.
- •Patients with BMI between 20 to 30 kg per m².
Exclusion Criteria
- •Severe spinal deformity.
- •Known allergy to local anaesthetics.
- •Systemic illnesses such as uncontrolled hypertension, diabetes, seizure disorder, cardiopulmonary disease.
- •Bleeding disorders, block site infection, hepatic or renal dysfunction.
- •BMI more than 30 kg per m².
- •Patients on anticoagulants/blood thinners.
- •History of head injury.
- •Psychiatric illness.
Outcomes
Primary Outcomes
Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in minutes or hours within 24 hours post surgery.
Time Frame: Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in baseline , 12th hr and 24th hr post surgery.
Secondary Outcomes
No secondary outcomes reported
Investigators
Mohammed Asjad T
Shri Sathya Sai Medical Collgege And Research Institute.