COMPARING CHROMOENDOSCOPY AND WHITE LIGHT VIDEO ENDOSCOPY FOR ESOPHAGEAL DYSPLASIA AND CANCER SURVEILLANCE IN PATIENTS WITH ACHALASIA

Recruiting

• Conditions: Esophageal motility disorder; movement disorder of the esophagus; 10017977

• Registration Number: NL-OMON30825
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

A) Age 18 years or older
B) Patients with primary achalasia as diagnosed according to standard criteria

Exclusion Criteria

A) Under 18 years of age
B) Known allergy against iodine
C) Hyperthyroidism
D) Esophageal varices
E) Barrett*s esophagus
F) Heart failure (New York Heart association III-IV)
G) Coagulopathy (prothrombin time < 50% of control; partial
thromboplastin time > 50 seconds) or anticoagulant use that can not be
discontinued

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary end point is the difference between WLE and CE for detection of<br /><br>dysplastic<br /><br>lesions or oesophageal carcinoma during gastroscopy in patients with achalasia.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Histological difference of the lesions detected only by WLE or only by CE<br /><br>- Duration of the procedure for WLE and CE</p><br>