Online Remote Behavioural Intervention for Tics (ORBIT)

Not Applicable

Completed

• Conditions: Tourette Syndrome or Chronic Tic Disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN70758207
• Lead Sponsor: ottinghamshire Healthcare NHS Foundation Trust

Brief Summary

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30610027 protocol 2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31898510 protocol (added 06/01/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34480868/ (added 06/09/2021) 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/35416566/ Comparison of tic symptoms before and during COVID-19 pandemic (added 14/04/2022) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36649686/ outcome results (added 18/01/2023) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37924247/ (added 06/11/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-20
• Study Completion: 2021-04-12
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 224

Inclusion Criteria

1. Aged 9 to 17 years
2. Suspected or confirmed Tourette syndrome/chronic tic disorder, including moderate/severe tics: score >15 on the Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score (TTSS); TTSS score>10 if motor or vocal tics only
3. Competent to provide written, informed consent (parental consent for child aged <16)
4. Broadband internet access and regular PC/laptop/Mac user, with mobile phone SMS

Exclusion Criteria

1. Previous structured behavioural intervention for tics e.g. HRT/CBIT or exposure and response prevention within last 12 months from baseline. Participants may start any new behavioural interventions for tics outside of the trial intervention only after the initial 6 months of the study
2. Change to medication for tics (starting or stopping medication) within the previous 2 months prior to baseline. Participants may start/change medication for tics only after the initial 6 months of the study
3. Diagnosis of alcohol/substance dependence, psychosis, suicidality, or anorexia nervosa
4. Moderate/severe intellectual disability
5. Immediate risk to self or others
6. Parent or child not able to speak or read English

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tic disorder symptoms assessed using the Yale Global Tic Severity Scale (YGTSS) - Total Tic score; Timepoint(s): Baseline, 3, 6, 12 and 18 months