Multiparametric Imaging for Analysis of MVNT (Multinodular and Vacuolating Neuronal Tumor)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 71
- Locations
- 7
- Primary Endpoint
- Description of a new radiological entity on Spectroscopy : the MVNT (Multinodular and Vacuolating Neuronal Tumor)
Study Overview
Brief Summary
Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.
Detailed Description
Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.
However, in order to avoid an invasive surgical procedure to remove the lesion, a certain diagnosis of its benignity is essential. The contribution of advanced techniques in MRI, such as spectroscopy in the characterization of these lesions, has not yet been studied today
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient over 18 years old
- •Suspicion of MVNT on an MRI: it is considered that it will be necessary at least the 2 major criteria associated with at least 1 minor criterion to enter the definition of suspicion of MVNT:
- •Major criteria:
- •Multinodular aspect in cluster
- •High FLAIR hypersignal / T2
- •Minor criteria:
- •Absence of mass effect
- •Hyposignal T1
- •Center of the lesion in hypsignal FLAIR or T1 hypersignal
- •Affiliate or beneficiary of a Social Security scheme
- •Having received informed information about the study and consenting to participate in the study
Exclusion Criteria
- •Patient benefiting from a legal protection measure
- •Pregnant or lactating woman
- •Contraindication to MRI
Outcomes
Primary Outcomes
Description of a new radiological entity on Spectroscopy : the MVNT (Multinodular and Vacuolating Neuronal Tumor)
Time Frame: 1 day
ratio of N-Acetylaspartate / Choline on Spectroscopy
Description of a new radiological entity on Spectroscopy : : the MVNT (Multinodular and Vacuolating Neuronal Tumor)
Time Frame: 1 day
area under curve of choline Spectroscopie
Secondary Outcomes
No secondary outcomes reported