NCT00942760已完成不适用
DMS-0901: Multimodal Magnetic Resonance Protocol to Distinguish Tumor Recurrence From Treatment-Related Necrosis in Patients With High Grade Gliomas
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- To prospectively acquire multiparameter MR variables at 1.5T and 3T MRI from treated high grade glioma patients to assign tissue signatures for tumor recurrence and radiation necrosis as established by pathologic examination.
研究概览
简要总结
Brain imaging tests are routinely used to detect the presence of a brain tumor or to evaluate the response to treatment. Sometimes the images obtained are not specific and the only way to establish a diagnosis is by obtaining a tissue sample. The hypotheses of the study is to determine if multimodal MR technique will provide tissue signatures that differentiate between tumor progression and treatment related necrosis in high grade glioma patients.
研究设计
- 研究类型
- Observational
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically proven high grae glioma with central pathology review at DHMC
- •Age 18 equal to or greater than 18 years
- •Karnofsky performance greater or equal to 60%
- •Patients must have received radiation therapy and chemotherapy but should not have received any anti-angiogenesis therapy.
排除标准
- •Any patient who requires urgent surgical resection of MRI abnormality would not be eligible
- •Pregnant women are not eligible
结局指标
主要结局
To prospectively acquire multiparameter MR variables at 1.5T and 3T MRI from treated high grade glioma patients to assign tissue signatures for tumor recurrence and radiation necrosis as established by pathologic examination.
时间窗: 24 months
次要结局
- To compare the predictive values of the multiparameter MR tissue signatures acquired at 1.5T and 3T(24 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Diagnostic use of magnetic resonance imaging and magnetic resonance arthrography for intra-articular pathologies of the hip joint – how often reasonable?OPS-Codes 3-805, 3-806, 3-826, 3-82a in combination with ICD M00.95, M13.15, M16.0, M16.1, M16.2, M16.3, M16.4, M16.5, M16.6, M16.7, M16.9, M24.05, M24.15, M24.25, M24.85, M25.55, M25.75, M65.95, M67.45, M85.45, M87.05, M87.15, M87.85, M94.85, M94.95, M99.85, M99.95, S79.8DRKS00011850KRH Klinikum Agnes Karll Laatzen203
已完成
2 期
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for GliomasBrain and Central Nervous System TumorsNCT00274755University of California, San Francisco250
Unknown
不适用
Role of MR Spectroscopy in Brain TumorsBrain NeoplasmsNCT03619694Assiut University100
撤回
不适用
Measuring Brain Tumor Consistency Using Magnetic Resonance ElastographyBrain NeoplasmNCT05516485University of Southern California200
终止
不适用
Comparing Magnetic Resonance Imaging/Spectroscopy TechniquesAbdominal Organs - LipodystrophyTumorsNCT00001219National Institutes of Health Clinical Center (CC)49,946