Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors

Not Applicable

Completed

• Conditions: Adult Brain Tumor; Brain Neoplasms
• Interventions: Diagnostic Test: PET imagery

• Registration Number: NCT03525080
• Lead Sponsor: Center Eugene Marquis

Brief Summary

For patient having a brain tumor, RMI is the standard exam for tumor characterization and determines initial surgery.

The aim of this study is to assess if PET could provide additional information that could have an impact on surgery (indication and planification)

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2018-05-02
• Study First Submitted QC: 2018-05-14
• Study First Posted: 2018-05-15
• Study Start: 2018-06-12
• Primary Completion: 2019-09-11
• Study Completion: 2019-09-11
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-23
• Last Update Posted: 2020-01-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Suspected glial resectable tumor
• Free and informed consent
• Affiliated to French social security

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Exclusion Criteria

• Suspected high grade glioma
• Surgical emergency
• Pregnant or breastfeeding woman
• Patient deprived of their liberty or under guardianship
• Patient not able to follow study medical monitoring for geographical, social or psychological reasons
• Treated with carbidopa, catechol-O-methyl transferase inhibitor, haloperidol, reserpine within 2 weeks before PET imagery

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
PET Arm	PET imagery	-

Primary Outcome Measures

Name	Time	Method
PET pictures and MRI sequences comparison	Imagings performed up to 29 days after inclusion (before brain surgery)	Comparison of PET pictures and MRI sequences will be done in order to assess concordance between both imagings

Trial Locations

Locations (1)

Centre Eugène Marquis; 🇫🇷 Rennes, Bretagne, France