Non-invasive Hemodynamic Monitoring During Blood Donation for Developing Models of Early Blood Loss
Completed
- Conditions
- Hemorrhage
- Interventions
- Other: No treatment
- Registration Number
- NCT01448694
- Lead Sponsor
- University of Colorado, Denver
- Brief Summary
This study is part of a Phase II STTR project to develop an algorithm called CipherSensor to apply feature extraction and machine learning techniques to non-invasive hemodynamic data to identify early signs of acute blood loss. The availability of this information may help to establish required interventions for treating trauma patients and battlefield casualties.
Study hypothesis: Hemodynamic changes measured non-invasively during the blood donation process can be modeled to provide early estimations of blood loss.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 320
Inclusion Criteria
- Approved by Children's Hospital Colorado Blood Donation Center for blood donation
- Age 18 -89 years
- Previously donated blood (lower likelihood of vasovagal response)
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Exclusion Criteria
- Pregnant
- Incarcerated
- Limited access to or compromised monitoring sites for non-invasive sensors: finger, ear and forehead sensors, oral/nasal cannula, 3 ECG electrodes.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Blood donors No treatment Healthy volunteers who are donating a pint of whole blood
- Primary Outcome Measures
Name Time Method Algorithm 24 months Mathematical model of early blood loss
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Children's Hospital Colorado
🇺🇸Aurora, Colorado, United States