From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests
Completed
- Conditions
- Pain
- Registration Number
- NCT01546480
- Lead Sponsor
- Odense University Hospital
- Brief Summary
Chronic Pain after Cholecystectomy is a well known problem. One theory is that it is due to persisting inflammation.
The purpose of the study is to measure inflammatory factors in cerebrospinal fluid and blod at patients 12 months after the operation.
DNA-samples are collected to examine genetical factors, important for perception of pain, and the development of chronic pain.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
- Unexplained abdominal pain 12 months after elective cholecystectomy
Read More
Exclusion Criteria
- Immunosuppressive treatment (NSAID excepted)
- Anticoagulant treatment
Group 2:
Inclusion Criteria:
- No pain 12 months after elective cholecystectomy
Exclusion Criteria:
- Immunosuppressive treatment (NSAID excepted)
- Anticoagulant treatment
Group 3:
Inclusion Criteria:
- Elective operation in spinal anesthesia or
- Or healthy volunteers accepting samples of blod, cerebral spinal fluid and saliva, to be collected
Exclusion Criteria:
- Acute or chronic pain condition
- Immunosuppressive treatment (NSAID excepted)
- Previous abdominal operation
Read More
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Spinal interleukine levels 12 months 12 months after surgery
- Secondary Outcome Measures
Name Time Method spinal enzyme levels 12 months 12 months after surgery
Blood interleukine levels 12 Months Blood enzyme levels 12 months 12 months after surgery
Trial Locations
- Locations (2)
Odense University Hospital
🇩🇰Odense, Denmark
Lillebælt Hospital
🇩🇰Vejle, Denmark