From Acute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy: The Significance of Components of Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Abdominal pain
研究概览
简要总结
Chronic Pain is a wellknown complication after cholecystectomy. Intensity of the pain in the first week after the operation is a predictive factor for the development of chronic pain, but it is unknown whether the risk is more related to one of the different components of acute pain (ie somatic, visceral, referred). Furthermore the chronic pain has not been systematically described in terms of type of pain or sensory abnormalities etc. (allodynia, hyperalgesia etc.).
The purpose of the study is to examine whether intensity of components of acute pain is predictive for development of chronic pain after cholecystectomy and to characterize the chronic pain by quantitative sensory testing.
DNA-samples are collected to examine genetical factors, important for perception of pain, and the development of chronic pain.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients for elective cholecystectomy
- •18 years or older at the day of the operation
- •Capable of speaking, reading and writing danish
排除标准
- •Previous abdominal operation
- •Patients with preoperative neuropathies
- •Patients with other diseases in the nervous system, preoperative paresthesias or other sensory disturbances.
结局指标
主要结局
Abdominal pain
时间窗: 12 months
次要结局
- Quantitative sensory testing values in referred pain area.(6 Months)
- Abdominal pain(6 months)
研究者
Morten Rune Eckhardt
Afdelingslæge, Ph.D.-student
Odense University Hospital