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Clinical Trials/NCT02745015
NCT02745015
Completed
Not Applicable

Effect of Non Surgical Treatment of Periodontitis on Glycaemic Control in a Type 2 Diabetic Populations of Cameroon

Yaounde Central Hospital1 site in 1 country45 target enrollmentDecember 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periodontitis
Sponsor
Yaounde Central Hospital
Enrollment
45
Locations
1
Primary Endpoint
Metabolic
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.

Detailed Description

The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.

Registry
clinicaltrials.gov
Start Date
December 2014
End Date
May 2015
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Yaounde Central Hospital
Responsible Party
Principal Investigator
Principal Investigator

Sobngwi Eugene

Professor

Yaounde Central Hospital

Eligibility Criteria

Inclusion Criteria

  • Type 2 diabetes for at least one year
  • periodontitis
  • HbA1c \> 7%

Exclusion Criteria

  • Periodontal treatment in the last 6 months
  • antibiotics in the last 3 months
  • tobacco smoking
  • pregnancy

Outcomes

Primary Outcomes

Metabolic

Time Frame: 3 months

Change in HbA1c

Secondary Outcomes

  • Inflammation(3 months)
  • Periodontal 1(3 months)
  • Periodontal 3(3 months)
  • Periodontal 2(3 months)

Study Sites (1)

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