Effects of Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles of Patients With an Indication for Surgical Coronary Revascularization
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Periodontitis
- Sponsor
- Universidade Veiga de Almeida
- Enrollment
- 22
- Primary Endpoint
- Glucose
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization.
Materials and Methods: Twenty-two patients with chronic periodontitis, over 35 years of age (mean age 59.45 years) randomly assigned into 2 groups were evaluated. Test group (n=11), received periodontal treatment before the surgical procedure, and control group (n=11), did not received periodontal treatment prior to surgery.
Investigators
Walmir Júnio de Pinho Reis Rodrigues
Researcher
Rio de Janeiro State University
Eligibility Criteria
Inclusion Criteria
- •Undergoing cardiovascular treatment;
- •Eight viable teeth in the oral cavity;
- •Four periodontal sites with periodontal probing depths ≥5mm in different teeth.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Glucose
Time Frame: Baseline and 90 days after the initial exam
Glucose showed a non-significant increase in the test group. Mean difference of 24.2 mg/dL.
Reduction in probing depth in sites with CAL >5mm
Time Frame: Baseline and 90 days after the initial exam
Reduction of 3.6% in probing depth in sites with Clinical Attachment Level \>5mm.
Leukocyte count
Time Frame: Baseline and 90 days after the initial exam
Non-significant reduction of leukocyte count in the test group. Mean difference of 74.6 m/mcL.
Reduction in probing depth in sites with PPD>3mm
Time Frame: Baseline and 90 days after the initial exam
Reduction of 11.4% in probing depth in sites with Periodontal Probing Depth\>3mm
Reduction in probing depth in sites with PPD>5mm
Time Frame: Baseline and 90 days after the initial exam
Reduction of 6.3% in probing depth in sites with Periodontal Probing Depth\>5mm
Reduction in probing depth in sites with CAL>3mm
Time Frame: Baseline and 90 days after the initial exam
Reduction of 4.6% in probing depth in sites with Clinical Attachment Level \>3mm.
Hemocyte
Time Frame: Baseline and 90 days after initial exam
Hemocyte presented a non-significant reduction in the test group. Mean difference 0.39 m/mcL
Hemoglobin
Time Frame: Baseline and 90 days after initial exam
Non-significant reduction in test group. Mean difference of 0.2 g/dL
Total Cholesterol
Time Frame: Baseline and 90 days after initial exam
Significant reduction in the test group. Mean reduction of 27.4 mg/dL.
High density lipid
Time Frame: Baseline and 90 days after initial exam
Significant reduction in test group. Mean difference of 8.2 mg/dL.
Low density lipid
Time Frame: Baseline and 90 days after initial exam
Non-significant reduction in test group. Mean difference of 8.9 mg/dL.