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Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles in Patients With Coronariopathies

Not Applicable
Completed
Conditions
Periodontitis
Coronariopathy
Interventions
Procedure: Periodontal treatment
Registration Number
NCT02150005
Lead Sponsor
Universidade Veiga de Almeida
Brief Summary

Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization.

Materials and Methods: Twenty-two patients with chronic periodontitis, over 35 years of age (mean age 59.45 years) randomly assigned into 2 groups were evaluated. Test group (n=11), received periodontal treatment before the surgical procedure, and control group (n=11), did not received periodontal treatment prior to surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Undergoing cardiovascular treatment;
  • Eight viable teeth in the oral cavity;
  • Four periodontal sites with periodontal probing depths ≥5mm in different teeth.
Exclusion Criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Periodontal treatmentPeriodontal treatmentThe test group received oral hygiene instructions, supragingival and subgingival scaling and root planning using curettes and an ultrasonic appliance.
Primary Outcome Measures
NameTimeMethod
Reduction in probing depth in sites with PPD>5mmBaseline and 90 days after the initial exam

Reduction of 6.3% in probing depth in sites with Periodontal Probing Depth\>5mm

Reduction in probing depth in sites with PPD>3mmBaseline and 90 days after the initial exam

Reduction of 11.4% in probing depth in sites with Periodontal Probing Depth\>3mm

Reduction in probing depth in sites with CAL>3mmBaseline and 90 days after the initial exam

Reduction of 4.6% in probing depth in sites with Clinical Attachment Level \>3mm.

Reduction in probing depth in sites with CAL >5mmBaseline and 90 days after the initial exam

Reduction of 3.6% in probing depth in sites with Clinical Attachment Level \>5mm.

Leukocyte countBaseline and 90 days after the initial exam

Non-significant reduction of leukocyte count in the test group. Mean difference of 74.6 m/mcL.

GlucoseBaseline and 90 days after the initial exam

Glucose showed a non-significant increase in the test group. Mean difference of 24.2 mg/dL.

HemocyteBaseline and 90 days after initial exam

Hemocyte presented a non-significant reduction in the test group. Mean difference 0.39 m/mcL

HemoglobinBaseline and 90 days after initial exam

Non-significant reduction in test group. Mean difference of 0.2 g/dL

Total CholesterolBaseline and 90 days after initial exam

Significant reduction in the test group. Mean reduction of 27.4 mg/dL.

High density lipidBaseline and 90 days after initial exam

Significant reduction in test group. Mean difference of 8.2 mg/dL.

Low density lipidBaseline and 90 days after initial exam

Non-significant reduction in test group. Mean difference of 8.9 mg/dL.

Secondary Outcome Measures
NameTimeMethod
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