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Clinical Trials/NCT07557459
NCT07557459
Not yet recruiting
Not Applicable

Access to Peri-implant Probing and Its Association With Peri-implant Diseases: A Multicenter Cross-Sectional Study

Arrow Development0 sites281 target enrollmentStarted: May 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Arrow Development
Enrollment
281
Primary Endpoint
Association between probing access and peri-implant radiographic bone loss

Overview

Brief Summary

This multicenter cross-sectional study aims to evaluate the association between access to peri-implant probing and radiographic peri-implant bone loss. Although probing is the primary diagnostic tool for peri-implant diseases, prosthetic design may limit access, potentially affecting diagnosis and disease progression. The study will include patients with dental implants in function for at least three years and will assess clinical, radiographic, and prosthetic variables.

Detailed Description

Peri-implantitis is a plaque-induced inflammatory condition characterized by inflammation of peri-implant tissues and progressive bone loss. Probing is essential for diagnosis; however, prosthetic design may hinder or prevent proper probing access, potentially compromising diagnostic accuracy.

Despite its clinical relevance, no studies have directly evaluated whether limited access to probing is associated with peri-implant bone loss. This study aims to address this gap.

This is a multicenter cross-sectional observational study conducted in nine private clinics in Spain. A total of 281 patients will be included. Clinical and radiographic data will be collected, including probing accessibility, probing depth, plaque index, bleeding on probing, suppuration, prosthetic design, hygiene accessibility, and radiographic bone levels.

Statistical analysis will evaluate associations between probing access and peri-implant bone loss at both patient and implant levels.

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Cross Sectional

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥18 years
  • Dental implants loaded for at least 3 years
  • Implant-supported restorations (single, partial fixed, or full-arch)
  • First visit to the clinic (maintenance, review, or treatment)
  • Signed informed consent
  • Availability of clinical and radiographic records

Exclusion Criteria

  • Exposure of the intraosseous portion of the implant
  • Evident prosthetic misfit
  • Inability to provide informed consent
  • Lack of cooperation for clinical examination

Outcomes

Primary Outcomes

Association between probing access and peri-implant radiographic bone loss

Time Frame: Baseline (cross-sectional assessment)

Evaluation of whether limited or impossible probing access is associated with increased radiographic bone loss (measured in mm from implant platform to bone level).

Secondary Outcomes

  • Prevalence of implants with limited or no probing accessibility(Assessed at the baseline visit (single cross-sectional evaluation))
  • Prevalence of non-hygienizable implant-supported prostheses(Assessed at the baseline visit (single cross-sectional evaluation))
  • Association between hygiene accessibility and peri-implant bone loss(Assessed at the baseline visit (single cross-sectional evaluation))
  • Clinical peri-implant parameters(Assessed at the baseline visit (single cross-sectional evaluation))
  • Patient-related and implant-related factors associated with probing accessibility(Assessed at the baseline visit (single cross-sectional evaluation))

Investigators

Sponsor
Arrow Development
Sponsor Class
Industry
Responsible Party
Principal Investigator
Principal Investigator

Alberto Ortiz Vigon

Principal Investigator, Dentist (DDS, PhD, MBA)

Arrow Development

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