A Multicenter, Randomized, Double-blind, Controlled trial of effects of using intravenous metoclopramide to increase mucosal visualization during endoscopy in patients with acute upper gastrointestinal bleeding
Phase 1
Recruiting
- Conditions
- Out-patient present in emergency department or in-patient has new inset upper gastrointestinal bleeding and received endoscopy within 24 hours of presentation or visited hospitalUGIB, UGIH, gastrointestinal hemorrhage, gastrointestinal bleeding, endoscopy, hematemesis, GI bleeding
- Registration Number
- TCTR20210708004
- Lead Sponsor
- avamindradhiraj university Research Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Out-patient present in emergency department or in-patient has new inset upper gastrointestinal bleeding and received endoscopy within 24 hours of presentation or visited hospital
Exclusion Criteria
History of metoclopramide allergy
Underlying disease of psychiatric problem, Parkinson disease, Abnormal movement, Chronic kidney disease more than stage 4
Pregnancy or breast feeding
Family history of Tardive dyskinesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clear mucosal visualization 10-30 mins Modified Avgerinos score
- Secondary Outcome Measures
Name Time Method Repeat endoscopy 72 hours Day of repeat endoscopy,Diagnostic cause of bleeding Within endoscopy Diagnostic cause during endoscopy,Side effect of metoclopramide 24 hours Clinical presentation