Clinical Trials
28
Trial Phases
3 Phases
Drug Approvals
31
Drug Approvals
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Clinical Trials
Distribution across different clinical trial phases (21 trials with phase data)• Click on a phase to view related trials
News
IO Biotech's Cylembio Plus Pembrolizumab Demonstrates Clinical Improvement in Advanced Melanoma Phase 3 Trial
IO Biotech's therapeutic cancer vaccine Cylembio combined with pembrolizumab achieved a median progression-free survival of 19.4 months versus 11.0 months with pembrolizumab alone in advanced melanoma patients.
IO Biotech's Melanoma Vaccine Narrowly Misses Primary Endpoint in Phase 3 Trial Despite Promising Subgroup Results
IO Biotech's cancer vaccine Cylembio combined with Keytruda showed a 23% relative risk reduction in disease progression or death compared to Keytruda alone, but narrowly missed statistical significance with a p-value of 0.056.
Iovance Biotherapeutics Withdraws Amtagvi EU Filing, Stock Plunges 29% Despite Strong Q2 Sales
Iovance Biotherapeutics voluntarily withdrew its European Union regulatory filing for Amtagvi due to lack of alignment with the EMA on clinical data supporting the submission.
GSK's TIM-3 Inhibitor Cobolimab Fails Phase III Trial in Advanced Lung Cancer
GSK's anti-TIM-3 monoclonal antibody cobolimab failed to improve overall survival in the Phase III COSTAR trial for advanced non-small cell lung cancer patients previously treated with immunotherapy.
Merck Announces $3 Billion Cost-Cutting Initiative to Prepare for Keytruda Patent Expiration
Merck plans to slash $3 billion in costs by the end of 2027 to reinvest in new product launches and drug pipeline development ahead of Keytruda's patent expiration in 2028.
Comprehensive Pipeline Analysis Reveals 200+ Investigational Drugs for Metastatic Hormone Refractory Prostate Cancer
A new comprehensive report analyzes over 200 pipeline drugs from 180+ companies targeting metastatic hormone refractory prostate cancer, highlighting the extensive research efforts in this challenging therapeutic area.
Leveragen and Propeller Bio Form Strategic Partnership to Advance Next-Generation Antibody Discovery Platform
Leveragen, a Boston-based biotech company, has announced a strategic collaboration with newly launched Propeller Bio to advance antibody and protein-based therapeutics development.
Absci Raises $50 Million to Advance AI-Driven Drug Discovery Platform and Internal Pipeline
Absci Corporation completed a $50 million public offering of 16.67 million shares at $3.00 per share to fund its AI-powered drug discovery programs and internal pipeline development.
Janux Therapeutics Advances Multi-Platform Pipeline with Novel ARM Technology for Autoimmune Diseases
Janux Therapeutics showcased its expanded immunotherapy pipeline at R&D Day, highlighting three proprietary platforms: TRACTr, TRACIr, and the novel ARM platform targeting autoimmune diseases.
Omega Funds Closes Oversubscribed $647M Fund VIII to Accelerate Life Sciences Innovation
Omega Funds successfully closed its eighth fund with $647 million in capital commitments, exceeding its $600 million target despite challenging fundraising conditions.