When to induce labour to limit risk in pregnancy hypertensio

Not Applicable

Completed

• Conditions: Chronic or gestational hypertension that develops by 37+6 weeks gestation; Pregnancy and Childbirth; Gestational [pregnancy-induced] hypertension

• Registration Number: ISRCTN77258279
• Lead Sponsor: King's College London

Brief Summary

2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/36271441/ Adaptations to trial during COVID pandemic (added 24/10/2022) 2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37019046/ (added 30/05/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2018-12-05
• Study Completion: 2024-01-31
• Last Update Posted: 10 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 403

Inclusion Criteria

1. Maternal age =16 years
2. Diagnosis of chronic or gestational hypertension
3. Singleton pregnancy
4. Live fetus
5. Gestational age of 36+0 to 37+6 weeks
6. Able to give written informed consent to participate

Exclusion Criteria

1. Contraindication to either one of the trial arms (e.g., evidence of pre-eclampsia)
2. Severe hypertension [i.e., blood pressure (BP) =160mmHg systolic or =110mmHg diastolic] until BP falls below this level (i.e. it is ‘controlled’)
3. Major fetal anomaly anticipated to require neonatal unit admission
4. Participation in another timing of delivery trial
NOTE: Women with co-morbidities (e.g., diabetes) and fetal size will not be exclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified