An 8 Weeks, Randomized, Double-blind, Placebo-controlled Clinical Trial for Anti-diabetic Effects of Hydrolyzed Ginseng Extract
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hyperglycemia
- Sponsor
- Chonbuk National University Hospital
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Changes of blood glucose during OGTT(oral glucose tolerance test)
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This study was conducted to investigate the effects of daily supplementation of hydrolyzed ginseng extract(HGE) on glycemic status in subjects with impaired fasting glucose(IFG).
Detailed Description
This study was a 8 weeks, randomized, double-blind, placebo-controlled trial. Twenty subjects were randomly divided into HGE or a placebo group. Fasting and postprandial glucose profiles during oral glucose tolerance test (OGTT) were assessed before and after the intervention.
Investigators
Soo-Wan Chae
Principal Investigator, Clinical Trial Center for Functional Foods
Chonbuk National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Age 20-70 years with fasting glucose 100\~126 mg/dL
Exclusion Criteria
- •Abnormal lipid profile values
- •Acute/chronic inflammation
- •Treated with corticosteroid within past 4 weeks
- •Cardiovascular disease
- •Allergic or hypersensitive to any of the ingredients in the test products
- •History of disease that could interfere with the test products or impede their absorption
- •Participation in any other clinical trials within past 2 months
- •Renal disease
- •Abnormal hepatic function
- •Under hypolipidemic drugs therapy within past 3 months
Outcomes
Primary Outcomes
Changes of blood glucose during OGTT(oral glucose tolerance test)
Time Frame: 8 weeks
Changes of fasting and postprandial glucose during OGTT were assessed before(baseline) and after the intervention.
Secondary Outcomes
- Changes of blood insulin during OGTT.(8 weeks)
- Changes of glycated albumin, fructosamine, and lipid profile(8 weeks)