Oral treatment of allergy with a non-pathogenic microorganism: A randomised clinical trial
- Conditions
- Allergic rhinitis.
- Registration Number
- JPRN-UMIN000001070
- Lead Sponsor
- Sponsor's representative: Mads Melbye, Executive Vicepresident, Statens Serum Institut, Dept. Epidemiology Research, Artillerivej 5, DK-2300 Copenhagen, Denmark
- Brief Summary
Journal of Allergy and Clinical Immunology. In press, September 2009. Title: Trichuris suis ova therapy for allergic rhinitis: A randomized double-blind placebo-controlled clinical trial. Authors: Bager P, et al.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
Significant asthma; Use of systemic steroids during the last 2 months; Immune therapy for grass pollen allergy the last 2 years; Planning a travel abroad during the trial period excluding areas with a similar grass or birch pollen counts when compared with the Copenhagen area; Past or current severe diseases eg a history of Crohns disease, ulcerative colitis, multiple sclerosis, active hepatitis B or C, cytomegalovirus, herpes simplex, HIV, other kinds of immune deficiency, and cancer; Anti-helminth treatment within the last 2 weeks; Known or possible hypersensitivity to Trichuris species or compounds made of Trichuris species; A past or recent drug abuse; Participation in other clinical trials; Employed with the Investigator, or the representative department at the sponsor institution
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method