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Investigating the effect of alpha lipoic acid on the amount of saliva in head and neck cancer patients undergoing radiotherapy

Phase 3
Recruiting
Conditions
Cancer patients undergoing cervical radiotherapy.
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Registration Number
IRCT20221219056864N1
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Age>18
Patients with head and neck cancers with a total radiation dose of 56-70 Gy

Exclusion Criteria

History of liver disease, diabetes, thyroid
History of alcohol consumption
Malnutrition
Receiving any chemotherapy drugs
History of salivary gland cancer
History of treatment with alpha-lipoid acid for any other reason
History of allergy to alpha-lipoid acid or other antioxidants and food supplements
Consumption of iron products
Pregnant or lactating women

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The effect of alpha-boic acid on the amount of saliva in cancer patients undergoing head and neck radiotherapy. Timepoint: Before starting radiotherapy and 2-6-8-12 weeks after radiotherapy. Method of measurement: Collection of unstimulated saliva in the Falcon tube within 5 minutes.
Secondary Outcome Measures
NameTimeMethod
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