Effect of Amniotic Membrane Dressing in Donor Graft Site

Not Applicable

Conditions: Patients suffered thermal burns in need skin graft.
Exposure to unspecified smoke, fire and flames

Registration Number: IRCT20200615047782N1

Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 36

Inclusion Criteria

Patients with second- or third-degree burns or patients who need a semi-thick skin graft for any other reason and have a donor site
Donor location in the limbs
No injuries other than burns
General physical and mental health
Age between 7 years and 60 years
Other conditions, such as trauma, are less than 40 percent of the wound and are on the limb and need to be removed

Exclusion Criteria

Patients with blood-borne viral infections including hepatitis B and C and HIV
Dissatisfaction of patients to enter the study
Lack of follow-up ability
Presence of any cerebrovascular, cardiovascular, endocrine, liver and kidney diseases; Pregnancy
History of alcohol and drug abuse
Concomitant use of antibiotics (orally and topically)
Concomitant use of steroids or immunosuppressive drugs
Infected patients at the donor site

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scar percentage. Timepoint: The amount of scar on the fifth, fourteenth, and finally thirty-sixth days is evaluated as outpatient in the clinic by the relevant professor and its amount is recorded with a qualitative scale of 4 items: excellent, good, average, weak. Method of measurement: A measure of the body's scar level that is measured objectively.;Healing rate. Timepoint: The time required for wound healing on the fifth, fourteenth, and finally 30th days of the clinic is evaluated on an outpatient basis by the relevant professor and its amount is recorded with a qualitative scale of 4 items: excellent, good, average, weak. Method of measurement: Healed: the wound area where the medicine wasapplied is completely healed ObviouslyEffective:70 % of the wound is healed Effective: over 30 % of the wound is healed Ineffective: the effective standard is not met.

Secondary Outcome Measures