Comparison of dressing with Amniotic membrane and Nitrofurazone ointment in second degree burn wound

Phase 2

Recruiting

• Conditions: superficial second-degree burns.; Calcification and ossification of muscles associated with burns, unspecified site; M61.30

• Registration Number: IRCT20181216041996N1
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 25 February 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

superficial second-degree burn in all age groups

Exclusion Criteria

unstable vital signs,
history of psychiatric disorders in patients with burns
smoking, drug and psychotropic substance addiction
history of heart, kidney, and liver diseases, diabetes, malnutrition,
history of corticosteroids or immunosuppressive drugs use,
inhalation and old burns
evidence of infection in burns
reaction and hypersensitivity to nitrofurazone ointment as well as to dressing with amniotic membrane
need for wound debridement in operation room
non-referral of patients after hospital discharge

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Wound infection. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation . examination.;, severity of pain in the dressing site. Timepoint: first 7 days. Method of measurement: The severity of pain was measured using Visual Analogue Scale 0 to 10 numeric pain distress scale- on which the patient left marks based on their pain sensation.;Level of epithelialization. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation.;Hospitalization period. Timepoint: hospitalization period. Method of measurement: observation.;Frequency of dressing changes. Timepoint: first 7 days. Method of measurement: observation.;Analgesic use. Timepoint: first 7 days. Method of measurement: observation.;Wound scarring rate. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: Vancouver scar score.