Assessment of the efficacy of amnion dressing in wound healing of skin graft donor sites
- Conditions
- Burn patients.Burn and corrosion of head, face, and neck
- Registration Number
- IRCT20210918052511N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 58
Patients between the ages of 15 and 55 are eligible to participate.
Have a severe burn of grade 2 or higher that requires a skin graft
Patients with burns that are less than or equal to 20%
Patient with deep second degree burns in upper and lower limbs and anterior trunk except lateral thigh
Patients who are receiving chemotherapy
Patients taking corticosteroids or cytotoxic medicines
Pregnancy
Cancer, cytotoxic drugs, immunosuppressants, and the presence of chronic diseases other than diabetes that affect wound healing, such as severe vascular disease, lupus, rheumatoid arthritis, and renal failure
Smoking
The presence of an underlying disease leads to a defective immune system
Diabetic patients
Taking drugs that lead to a defective immune system.
Burns in the lateral thigh area.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of complete wound healing. Timepoint: Every 48 hours. Method of measurement: Based on the clinical observations of an infectious disease specialist and plastic and burn surgeon.
- Secondary Outcome Measures
Name Time Method Wound condition, including the presence or absence (yes/no) of granulation tissue, bleeding, pain, infection, and other wound complications or healing factors are evaluated. Timepoint: Every 48 hours. Method of measurement: Based on the scores of the variables and presence or absence (yes / no).