NCT05811689
Completed
Not Applicable
Trabecular Bone Score (TBS) as an Innovative Parameter Evaluation for Bone Disease's in Multiple Sclerosis (MS) Patients and Impact of Osteoporosis on the Quality of Life of Patients With MS
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- IRCCS Centro Neurolesi "Bonino-Pulejo"
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- DXA scanner (Horizon© DXA System)
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Assess bone quality in MS patients through TBS and evaluate the potential effects exerted by different drugs used in MS treatment, which may affect BMD and TBS in MS patients
Investigators
Eligibility Criteria
Inclusion Criteria
- •diagnosis of MS according to the latest revision of McDonald's criteria;
- •patients with relapsing-remitting MS (RRMS), secondary progressive MS (SPMS) and primary progressive MS (SPMS);
- •absence of cortisone therapy for at least 6 months;
Exclusion Criteria
- •patients already being treated with anti-osteoporotic drugs;
- •medical conditions that preclude the execution of the densitometric examination
Outcomes
Primary Outcomes
DXA scanner (Horizon© DXA System)
Time Frame: 6 months
The DXA scanner (Horizon© DXA System) measures bone mineral content relative to bone area.
Secondary Outcomes
- Bone Mineral Density(6 months)
Study Sites (1)
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