Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee.

Not Applicable

Completed

• Conditions: Osteo Arthritis Knee
• Interventions: Behavioral: Mulligan's mobilization with movement MWM added isometric strength training

• Registration Number: NCT05577403
• Lead Sponsor: Majmaah University

Brief Summary

To evaluate the effect of Mulligan's mobilization with movement in osteoarthritis of the knee.

Detailed Description

Patients with knee OA diagnosed at the orthopaedic clinic of Tumair general hospital and referred to the physiotherapy department who attended the rehabilitation centre of Majmaah university will be recruited.

Patients will be excluded if they had knee or hip injury, sensory deficits in the lower extremity, a history of lower-extremity surgery, or a history of a quadriceps or hamstring muscle injury, had low back-related leg pain, or had any contraindication to manual therapy.

The protocol was submitted to and approved by the Majmaah University Research Ethics committee (MUREC Dec.2/ COM-2021/19-3)

Participants will be requested to sign a written informed consent form approved by the institutional ethics committee. A total of 60 participants were randomly assigned to group A (experimental group): Mulligan's mobilization with movement MWM added isometric strength training, and group B (control group): Sham MWM added isometric strength training. Pre and post-test readings were taken at baseline, week 2, and week 4, respectively. The outcome measures for this study will be maximal voluntary isometric contraction of quadriceps strength (measured by ISOMOVE dynamometer), ROM, and Western Ontario and McMaster universities osteoarthritis (WOMAC) index.

Study Timeline

• Study First Submitted: 2021-12-07
• Study First Submitted QC: 2022-10-10
• Study First Posted: 2022-10-13
• Study Start: 2022-11-05
• Status Verified: 2023-11
• Primary Completion: 2023-11-10
• Study Completion: 2023-11-14
• Last Update Submitted: 2023-11-14
• Last Update Posted: 2023-11-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patient with knee OA with radiological evidence of grade 2 or 3 of the Kellgren and Lawrence scale.
• Age between 40-65 years, unilateral or bilateral involvement (in the case of bilateral involvement, the more symptomatic knee was included), and pain in and around the knee.

Exclusion Criteria

• Patient will be excluded, if they had any deformity of the knee, hip, or back, had any central or peripheral nervous system involvement.
• They had received steroids or intra-articular injection within the previous three months, uncooperative patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental Group	Mulligan's mobilization with movement MWM added isometric strength training	Mulligan's mobilization with movement added isometric strength training will be given 3 days a week for six weeks.
Control Group	Mulligan's mobilization with movement MWM added isometric strength training	Mobilization-added isometric strength training will be given 3 days a week for six weeks.

Primary Outcome Measures

Name	Time	Method
pain intensity	6 weeks	Visual Analogue scale on 0 to10 cm
Range of Motion	6 weeks	Standard goniometer.
Western Ontario and McMaster universities osteoarthritis (WOMAC) index	6 weeks	Western Ontario and McMaster universities osteoarthritis scale

Trial Locations

Locations (1)

Rehabilitation center, Majmaah University; 🇸🇦 Al Majma'ah, Riyadh, Saudi Arabia