Compression of intranasal ketamine, intranasal fentanyl adjunct to intravenous ketorolac on renal colic pain relief

Phase 3

Recruiting

• Conditions: Unspecified renal colic; renal colic.

• Registration Number: IRCT20201028049179N1
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 November 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

All patients suspected for renal colic and urolithiasis based on urine analysis and imaging (ultrasonography or CT scan), history and physical examination.
Age between 15 to 64

Exclusion Criteria

Pregnancy
Addiction to opioids and psychedelics
Allergy to fentanyl, ketamine and ketorolac
Fever (body temperature more than 38°C) and suspicion of pyelonephritis
Systolic blood pressure above 180 mm Hg or below 90 mm Hg, respiratory rate below 12 per minute and heart rate above 140 or below 60
History of liver, renal or cardiovascular disease, active peptic ulcer, brain tumors, glaucoma and psychosis
Consumption of analgesic drugs in the last 4 hours
VAS score below 5
Congestion of both nostrils

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of renal colic pain according to Visual Analogue Scale score. Timepoint: Initiation of study and 5, 10, 15, 30 and 60 minutes after prescription medication. Method of measurement: Visual Analogue Scale.