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Does decreasing the dose of remifentanil gradually at the end of a child's tonsillectomy operation rather than stopping it abruptly effect pain afterthe operation?

Phase 1
Conditions
Tonsillectomy and adenotonsillectomy
Therapeutic area: Diseases [C] - Ear, nose and throat diseases [C09]
Registration Number
EUCTR2019-001677-81-NO
Lead Sponsor
Akershus Universitetssykehus
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

American Society Anaesthesiology I-II children 1 to 10 years Weight over 10.0 Kg
Undergoing day case tonsillectomy or adentonsillectomy at Akershus Universitetssykehus, Lørenskog, Norway
Are the trial subjects under 18? yes
Number of subjects for this age range: 60
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Children who have had airway surgery previously.
Children who have had any type of surgery in the previous 12 monhts. Children using chronic pain medication or who have used analgesia in the 24 hours preceeding surgery.
Children who are known to suffer from NSAID sensitive asthma. Children with a known allergy to propofol or remifentanil.
Pre-existing cardiac, renal, liver dysfunction.
Children or parents who are not fluent in Norwegian or English. Children in whom more than three attempts at intravenous cannulation are required or in those who request an inhalational induction or premedication.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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