Effects of Exercise Training on Markers of Lung Inflammation and Clinical Crontrol in Asthma Children
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 36
- Locations
- 1
- Primary Endpoint
- Exhaled Nitric Oxide (FeNO) Level
Study Overview
Brief Summary
The purpose of this study is to assess the effects of a physical training program with active video game in inflammatory markers, quality of life variables , clinical control and physical and functional respiratory assessment of asthmatic children from 5 to 11 years.
Detailed Description
The aim of the present study will be to determine whether an aerobic exercise using an active video game system improves asthma control, lung inflammation and functional capacity in children with moderate or severe asthma.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 5 Years to 11 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Ages 5 to 11 years;
- •Having a diagnosis of asthma, according to the criteria of the National Heart, Lung, and Blood Institute, and
- •Not be included in any program of regular physical activity.
Exclusion Criteria
- •Having received aminophylline and theophylline or oral corticosteroids in the last 30 days;
- •Respiratory infection have shown over the past two months;
- •Have done with inhaled bronchodilator in less than 12 hours before the assessment;
- •Inability to perform any of the tests;
- •Have heart disease of inflammatory origin, congenital or ischemic;
- •Being in the presence of any infectious process with fever and
- •Do not agree to the terms of consent
Arms & Interventions
Aerobic exercise
The aerobic training will be done on the treadmill with heart monitors with intensity required to achieve 70% of maximum heart rate reached the maximum test for thirty minutes.
Intervention: Aerobic exercise group (Other)
Video game
The training with video game will be done with heart rate monitors with intensity required to achieve 70% of maximum heart rate reached the maximum test for thirty minutes.Will be used Kinect games ( reflex ridge- Adventure).
Intervention: Video game group (Other)
Outcomes
Primary Outcomes
Exhaled Nitric Oxide (FeNO) Level
Time Frame: The FeNO level was performed in week 8
The measurement of exhaled FeNO level is performed by several commercially available devices, however the equipment NIOX ® (Aerocrine, Sweden) analyzer is the only FDA-approved and Anvisa (Food and Drug Administration) for clinical monitoring of asthma. The measure will be performed before and after the training program of exercise, or pulmonary rehabilitation, by means of portable equipment NIOX MINO ®.
Secondary Outcomes
- Treadmil Test (Bruce Protocol)(8 week distance walked on treadmill test)
- Body Composition(baseline and after 8 weeks)
- Pulmonary Function(baseline and after 8 weeks)
Investigators
Evelim Leal de Freitas Dantas Gomes, PhD
PhD in science Rehabilitation
Hospital Sirio-Libanes