Effects of Exercise Training Amount and Intensity on Cardiovascular Disease Risk Factors in Middle-Age Men and Women at Risk for Cardiovascular Disease

Not Applicable

• Conditions: cardiovascular disease; physical inactivity; Type 2 diabetes; Cardiovascular - Coronary heart disease; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12613000583741
• Lead Sponsor: The University of Auckland - Faculty Research Development Fund (FRDF) New Staff Grant

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-05-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Overweight or obese (body mass index – BMI between 25-40 kg/m2); resting systolic blood pressure (SBP) of 110-159 mmHg and a resting diastolic blood pressure (DBP) less than or equal to 99 mmHg; clinically stable and have no known metabolic diseases; not performing regular physical activity – defined as completing no more than 20 minutes of structured exercise, 2 days/wk, at any time during the previous 6 months.

Exclusion Criteria

Participants will be excluded if they are already physically active; have terminal illness; a psychiatric disorder, have significant exercise limitations; or evidence of CVD.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VO2max assessed via indirect calorimetry during a graded maximal exercise test on a treadmill. [12 weeks after randomisation];Insulin resistance assessed via serum assay using the HOMA model. [12 weeks after randomisation]

Secondary Outcome Measures

Name	Time	Method
waist circumference[12 weeks after randomisation];The lipid profile will be assessed via serum assay. [12 weeks after randomisation]