JPRN-jRCT2041220154招募中2 期
Randomized phase II study comparing efficacy and safety of alpha fetoprotein derived peptides to placebo for the patients with advanced hepatocellular carcinoma after transarterial chemoembolization for hepatocellular carcinoma
Mizukoshi Eishiro0 个研究点目标入组 84 人开始时间: 2023年3月2日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 84
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1) clinically diagnosed as hepatocellular carcinoma
- •2) unsuitable for local therapy and treated by TACE
- •3) recoverd by adverse events due to TACE
- •4) HLA (Human Leukocyte Antigen) -A24
- •5) Child-Pugh classification A or B
- •6) 20 years or older
- •7) ECOG Performance status <=2
- •8) preservation of major organ function
- •9) written informed consent
排除标准
- •1) refractory ascites or pleural effusion
- •2) encephalopathy within 3 months
- •3) risky varices
- •4) active double cancer
- •5) pregnant or lactating women, or women of childbearing potential
- •6) mental disorder
- •7) previously treated by AFP peptide or adjuvant
- •8) allergy for AFP peptide or adjuvant
- •9) previously treated by immunotherapy
- •10) allergy for contrast agents for CT and MRI
- •11) patients who investigator regards as inappropriate for candidate
研究者
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