NCT00169572已完成2 期
See Detailed Description
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 492
- 试验地点
- 52
- 主要终点
- The number of subjects who do not experience vomiting, retching or nausea over a 5 day period following the initiation of chemotherapy.
研究概览
简要总结
This study was designed to assess the safety and efficacy of an investigational agent administered in addition to a standard anti-emetic regimen for the treatment of chemotherapy induced nausea and vomiting.
详细描述
Phase II Multicentre, Randomised, Double-Blind, Placebo and Active-Controlled, Dose-Ranging, Parallel Group Study of the Safety and Efficacy of The Oral Neurokinin-1 Receptor Antagonist, GW679769 in Combination with Ondansetron Hydrochloride and Dexamethasone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Cancer Subjects Receiving Highly Emetogenic Cisplatin-based Chemotherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
The number of subjects who do not experience vomiting, retching or nausea over a 5 day period following the initiation of chemotherapy.
次要结局
- Routine physical exam findings, vital signs, routine clinical laboratory tests, clinical monitoring and/or observation, and adverse events reporting.
研究者
研究点 (52)
Loading locations...
相似试验
已完成
1 期
SGI-110 Plus Durvalumab/Tremelimumab in SCLCExtensive-stage Small Cell Lung CancerNCT03085849Catherine Shu2
已完成
不适用
A Clinical Trial to Evaluate Efficacy and Safety of a Water-soluble Head Lice Product.Head LicePediculosis CapitisNCT03617926Oystershell NV70
已完成
3 期
Efficacy and Safety of Increased Dose of TA-650 (Infliximab) in Patients With Crohn's Disease (CD)Crohn's DiseaseNCT00805766Tanabe Pharma Corporation39
进行中（未招募）
不适用
Ensayo clínico para evaluar la eficacia y seguridad de la rapamicina en los angiomiolipomas en pacientes con esclerosis tuberosaClinical Trial to Determine the Efficacy and Safety of Rapamycin in Angiomyolipomas in Pacients with Tuberous SclerosisAngiomiolipomas en pacientes con esclerosis tuberosa (angiomyolipoma of tuberous sclerosis patients)MedDRA version: 9.1Level: LLTClassification code 10045138Term: Tuberous sclerosisEUCTR2007-005978-30-ESFUNDACIÓ PUIGVERT
招募中
1 期
Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed GlioblastomaGlioblastomaNCT04443010Philogen S.p.A.226