MedPath

GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months

Phase 2
Not yet recruiting
Conditions
Malaria
Interventions
Biological: RTS,S/AS01E vaccine
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
238
Registration Number
NCT07036159
Locations
🇷🇼

Center for Family Health Research, Kigali, Rwanda

🇷🇼

Rinda Ubuzima Gatenga Medicalized Health Center University of Rwanda, Kigali, Rwanda

A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)

Phase 3
Not yet recruiting
Conditions
Meningitis
Interventions
Biological: rMenB+OMV NZ vaccine
First Posted Date
2025-05-29
Last Posted Date
2025-05-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
312
Registration Number
NCT06995430

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

Phase 1
Recruiting
Conditions
Neoplasms, Prostate
Interventions
Drug: GSK5458514
First Posted Date
2025-05-25
Last Posted Date
2025-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
82
Registration Number
NCT06990880
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GSK3862995B Administered as a Single Dose to Healthy Participants of Chinese, Japanese, and European Ancestry

Phase 1
Not yet recruiting
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: GSK3862995B
Drug: Placebo
First Posted Date
2025-05-20
Last Posted Date
2025-05-20
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
30
Registration Number
NCT06979518

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

Phase 3
Recruiting
Conditions
Asthma
Interventions
First Posted Date
2025-05-18
Last Posted Date
2025-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
150
Registration Number
NCT06979323
Locations
🇺🇸

GSK Investigational Site, Plantation, Florida, United States

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

Phase 3
Not yet recruiting
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Placebo
First Posted Date
2025-05-07
Last Posted Date
2025-05-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
960
Registration Number
NCT06961214

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)

Phase 3
Recruiting
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Placebo
First Posted Date
2025-05-06
Last Posted Date
2025-07-01
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
981
Registration Number
NCT06959095
Locations
🇺🇸

GSK Investigational Site, Miami, Florida, United States

All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma

Phase 3
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
First Posted Date
2025-05-04
Last Posted Date
2025-06-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
21
Registration Number
NCT06956170
Locations
🇯🇵

GSK Investigational Site, Hokkaido, Japan

🇯🇵

GSK Investigation Site, Fukushima City, Fukushima-Ken, Japan

Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) - Sub-study 3

Phase 2
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2025-04-14
Last Posted Date
2025-07-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
62
Registration Number
NCT06926673
Locations
🇺🇸

GSK Investigational SIte, Nashville, Tennessee, United States

🇪🇸

GSK Investigational Site, Malaga, Spain

A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)

Phase 4
Not yet recruiting
Conditions
Neoplasms, Endometrial
Interventions
First Posted Date
2025-03-27
Last Posted Date
2025-03-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
100
Registration Number
NCT06897527
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