Comparing cyanoacrylate tissue adhesives and absorbable sutures in donor sites of connective tissue grafts (CTG) for primary closure.

Phase 4

Completed

• Conditions: Chronic periodontitis,; Systemically healthy individuals with miller’s Class I and Class II recession needing recessioncoverage.

• Registration Number: CTRI/2020/12/030104
• Lead Sponsor: Terna Dental College

Brief Summary

This is a Randomised Clinical Trial to compare between cyanoacrylate tissue adhesives and absorbablesutures in primary closure of donor sites of connective tissue grafts (CTG)  that willbe conducted in Terna Dental College, India. The primary outcome will beto measure primary wound closure at palatal donorarea in patients undergoing sub-epithelial connective tissue grafts (CTG).

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-01
• Study Completion: 2022-01-28
• Last Update Posted: 2022-02-15

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• Full Mouth Plaque Score and Full Mouth Bleeding Score needed to be <20% 2.
• Patients with miller’s Class I and Class II recession needing recession coverage.
• Patients between the age group of 18 – 60 yrs.
• Patients maintaining good oral hygiene.
• Systemically healthy patients.
• Patients who give informed consent to participate in the study.
• Patients who do not consume tobacco in any form.

Exclusion Criteria

• Patients who have undergone any periodontal surgical therapy in the last 6 months in the same site.
• Patients taking anticoagulants and anti-platelet drugs 3.
• Patients with allergies to materials used in treatment process.
• Pregnant and lactating females.
• Patients with coagulation disorders (e.g. Hemophilia a/b, von Willebrand disease, liver disease) 6.
• Patients on corticosteroids.
• Patients with a history of contact dermatitis to formaldehyde.
• Patients who have uncontrolled diabetes.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure and compare primary wound closure at palatal donor	Baseline | 1 day | 7 day
area in patients undergoing sub-epithelial connective tissue grafts (CTG)	Baseline | 1 day | 7 day
between cyanoacrylates tissue adhesives and absorbable suture.	Baseline | 1 day | 7 day

Secondary Outcome Measures

Name	Time	Method
To measure and compare the time taken for wound closure, Early Wound	Healing Index and Patient pain and discomfort at palatal donor area of

Trial Locations

Locations (1)

TPCTs Terna Dental College; 🇮🇳 Thane, MAHARASHTRA, India

TPCTs Terna Dental College

🇮🇳Thane, MAHARASHTRA, India

Dr Kashmira Ghangrekar

Principal investigator

9930660555

kashmira.ghangrekar@gmail.com