Immunological response after early extra and regular MMR immunization; 10 years follow-up

Recruiting

• Conditions: Measles infection; paramyxovirus; 10047438

• Registration Number: NL-OMON56402
• Lead Sponsor: RIVM

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

• Participation in the study on the immunological effects of early extra
measles vaccination, as described in a separate study protocol
(NL45616.094.13/IIV-273) or participation in the BMR-nul questionnaire study
• The parents/legally representatives accept participation in the trial
according to the described procedures
• Presence of an informed consent signed by both parents/legal representatives
• Children must have received the MMR-2 vaccination

Exclusion Criteria

• Presence of a serious disease that requires medical care that can interfere
with the results of the study
• Known or suspected immunological disorder
• Bleeding disorders

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Measles specific serum IgG and virus neutralizing antibodies 2 years (+/- 2<br /><br>months) after MMR-2 vaccination.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Serum IgG antibody concentrations against mumps and rubella 2 years (+/- 2<br /><br>months) after MMR-2 vaccination. </p><br>