Immunological response after early extra and regular MMR immunization; 6 years follow-up
- Conditions
- Measles infection, paramyxovirus
- Registration Number
- NL-OMON26839
- Lead Sponsor
- RIVM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 105
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•Participation in the study on the immunological effects of early measles vaccination, as described in a separate study protocol (NL45616.094.13/IIV-273)
•The parents/legally representatives accept participation in the trial according to the described procedures
•Presence of a signed informed consent
•Children must have received their NIP vaccinations according to schedule.
A potential subject who meets any of the following criteria will be excluded from participation in this study:
•Receiving immunosuppressive medication
•Presence of a serious disease that requires medical care that can interfere with the results of the study
•Known or suspected immunological disorder
•Bleeding disorders
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the effect of early extra measles immunization on the humoral immunity against measles 6 years after<br>MMR-1 at 14 months of age
- Secondary Outcome Measures
Name Time Method •Determine the effect of early extra measles immunization on the immunity against mumps and rubella 6 years after<br>MMR-1 at 14 months of age<br>•Determine the effect of early extra measles immunization on the immunity against other NIP vaccines 6 years after<br>MMR-1 at 14 months of age