Incidence and risk factors related to meningitis ocuring after neurosurgical operatio

Not Applicable

Conditions: Health Condition 1: B95-B97- Bacterial and viral infectious agentsHealth Condition 2: A498- Other bacterial infections of unspecified site

Registration Number: CTRI/2018/09/015743

Lead Sponsor: Shilpa Sundar

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.All post-operative patients [including all craniotomies (both tumor and trauma), endonasal procedures, procedures involving placement of implants or drains] under the Department of Neurosurgery who have been newly diagnosed with meningitis confirmed by CSF cultures and biochemical investigations,

2.Patients who develop infection within 30 days of primary surgery

3.Patients who have survived for more than 72 hoursâ?? post-surgery,

4.Patients who have undergone a redo surgery because of a direct cause or result of the primary surgery, within 30 days from the primary surgery.

Exclusion Criteria

1.Patients who underwent surgery outside the institution (Department of Neurosurgery, Kasturba Hospital, Manipal),

2.Patients who develop infection after 30 days of primary surgery,

3.Patients below 18 years of age,

4.Patients diagnosed with non-CNS infection prior to primary surgery,

5.Patients without positive CSF culture and biochemical investigations.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Study exposure variables: Glasgow Coma Scale (GCS), CSF studies â?? culture reports and biochemical profile, Neuro imaging â?? CT Brain (Plain and contrast) and MRI Brain, Antibiotic spectrum. <br/ ><br>Study Outcome Variables: Drop in GCS, focal or diffuse neurological deficit, seizures and any form of neurological obtundation post-surgery ; Setting up a microbiological spectrum and Antibiotic protocol for postoperative neurosurgical patients with meningitis.Timepoint: at the end of follow up of each patient

Secondary Outcome Measures