MedPath

Japan colorectal tumor prevention study

Phase 2
Conditions
colorectal tumor
Registration Number
JPRN-jRCTs061180079
Lead Sponsor
Takayama Tetsuji
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
600
Inclusion Criteria

Candidate patients have to meet all the following inclusion criteria to participate in the study.
# Patients with at least one colorectal tumor (intramucosal cancer and adenoma) as confirmed by histological diagnosis, all of which have been removed endoscopically (at any time)
# Patients with known history of all endoscopic treatments (including histological diagnosis) of colorectal tumors
# Patients who have undergone total colonoscopy at least twice
# Patients with clean colon as confirmed by total colonoscopy within 3 months before the study

Exclusion Criteria

# Patients with a medical history of submucosal or deeper colorectal cancer.
# Patients currently taking antithrombotics such as Bayaspirin, Bufferin, Panaldine, Warfarin, Persantin and NOAC.
# Patients who have undergone colorectal resection (those who have undergone appendectomy are allowed to participate in the study).
# Patients with familial colorectal adenoma.
# Patients with any existing cancer at the time of participation in the study.
# Patients with known allergy to curcumin.
# Patients currently taking anticancer drugs.
# Women who are or may be pregnant during the study period.
# Patients currently taking NSAIDs at least 3 times weekly, for example, as a analgesic.
# Patients with ulcerative colitis or Crohn's disease
# Patients with bleeding tendency or platelet count less than 70,000.
# Patient taking turmeric as a supplement.
# Patient deemed inappropriate by a doctor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The occurrence of a colorectal tumor (adenoma or cancer) is selected as the primary endpoint.
Secondary Outcome Measures
NameTimeMethod
# questionnaire<br># The occurrence of tumor (adenoma or cancer) with exception of colon
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