Phase I/II study of prevention of Colorectal Cancer CRC with Allopurinol in High-Risk Subjects - APAC

AZIENDA OSPEDALIERA OSPEDALI GALLIERA0 个研究点目标入组 75 人开始时间: 2007年3月1日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•1.Age 8805; 18 years, 75 years; 2.Provision of written informed consent; 3.Subjects with one ore more colorectal adenomatous polyps diam. 8805; 1 cm ; 4.Adequate renal and hepatic function; 5.Performance status 8804; 1;
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Presence of iperplastic polyps and/or flat adenomas; Subjects with pre-existing CCR; Presence of carcinoma tissue in adenoma; Previous allopurinol assumption within 6 months ; Pregnancy or breast feeding women of child-bearing potential must have a negative pregnancy test within 7 days before the start of study treatment ; Known severe hypersensitivity to allopurinol or any of the excipients of this product; Geographic inaccessibility or proven difficulty to assure adequate compliance; Renal failure grade 1 creatinine 1.5 x ULN ; Acute Gout; Subjects in anticoagulant therapy with dicumarol.

发起方

AZIENDA OSPEDALIERA OSPEDALI GALLIERA