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Clinical Trials/NCT04656743
NCT04656743
Completed
Not Applicable

Comparison of Genicular Nerve Block and Intraarticular Injection for Postoperative Pain in Knee Arthroscopy

Tanta University1 site in 1 country66 target enrollmentDecember 10, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Tanta University
Enrollment
66
Locations
1
Primary Endpoint
first time of rescue analgesia
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This prospective double-blinded randomized study will be conducted to compare ultrasound-guided intra-articular injection and ultrasound-guided genicular nerve block for postoperative analgesia after knee arthroscopy.

Detailed Description

Arthroscopic knee surgery has become increasingly popular in modern orthopedics. Post-operative knee pain management has become a challenge to provide early relief and pain-free postoperative care to the patient. Pain management has become a priority for management as a daycare procedure. Patients operated as a daycare procedure should have minimal postoperative pain which influences the timing of discharge. Pain is due to multifactorial causes such as irritation of free nerve endings of the joint capsule, synovial tissue, anterior fat pad. Effective pain relief allows the patients to obtain early knee mobilization and optimal rehabilitation and thus improves patient satisfaction. Postoperative pain after knee arthroscopy is commonly moderate to severe and can affect the patient's activity level and satisfaction. In an effort to provide safe, effective, and long-lasting post-arthroscopy pain relief, many drug regimens were injected intra-articularly including local anesthetics alone or with additive drugs to prolong and improve the quality of postoperative analgesia. Genicular nerve block (GNB) and ablation have been used for managing chronic pain from knee osteoarthritis with good success.

Registry
clinicaltrials.gov
Start Date
December 10, 2020
End Date
April 15, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

tarek abdel hay mostafa

principle investigator

Tanta University

Eligibility Criteria

Inclusion Criteria

  • scheduled for unilateral knee arthroscopy surgery (ligament reconstruction, cartilage procedures, and diagnostic arthroscopic procedures)
  • aged between 18 and 50 years
  • of both genders,
  • have ASA physical status I and II.

Exclusion Criteria

  • Revision knee arthroscopy,
  • previous surgery or trauma to the knee,
  • drug allergy,
  • regular narcotic use,
  • renal \&/ or hepatic impairments,
  • neuromuscular diseases
  • and coagulopathy disorders.

Outcomes

Primary Outcomes

first time of rescue analgesia

Time Frame: postoperative first day

first time of rescue morphine analgesia

Secondary Outcomes

  • Total doses of postoperative morphine consumption(postoperative first day)
  • Number of patients received rescue analgesia.(postoperative first day)

Study Sites (1)

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