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Clinical Trials/NCT04864912
NCT04864912
Completed
Not Applicable

A Retrospective Mapping of Health Care Utilisation and Current Quality of Life Status in Adult Subjects With a History of Chronic Otitis Media With or Without Cholesteatoma Who Have Undergone a Primary Tympanoplasty

Cochlear6 sites in 3 countries69 target enrollmentFebruary 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Otitis Media
Sponsor
Cochlear
Enrollment
69
Locations
6
Primary Endpoint
Number and Type of Contacts With Health Care Providers
Status
Completed
Last Updated
last year

Overview

Brief Summary

The objective of this multicentre study is to evaluate the standard of care of participants diagnosed with Chronic Otitis Media that have already gone through a first middle ear surgery but still have at least a moderate hearing loss. The study has a retrospective part (extraction of medical chart data) and a prospective part with a survey and three questionnaires collecting data on the use of health care services, on health related quality of life and hearing performance.

Registry
clinicaltrials.gov
Start Date
February 1, 2022
End Date
October 9, 2023
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Cochlear
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult subjects, 18 years or older.
  • Subjects with conductive or mixed hearing loss.
  • Subjects with historically documented diagnosis of Chronic Otitis Media (COM) with or without cholesteatoma in the operated ear.
  • Subjects who have undergone primary tympanoplasty type I-V to improve hearing between 2010-
  • Subjects with a Pure Tone Average (PTA)4 air-bone gap ≥30 decibels (dB) OR PTA4 air-bone gap between 25-30 dB with an air conduction threshold PTA4 ≥40 dB HL within 12 months after primary tympanoplasty in the operated ear.
  • Subjects who have been recommended by their health care professional to try a hearing aid to improve hearing in the operated ear.
  • Pre-op audiogram, maximum 1 year prior to the primary tympanoplasty, and post-op audiogram for the primary tympanoplasty are available.
  • Aided audiogram, unaided if no hearing device is used, available between 2018 and the point of enrolment.
  • Subjects are fluent in the language used for study questionnaires: German, French, Spanish.
  • Subjects are willing and able to provide written informed consent. For France: subjects do not oppose to participate in the study.

Exclusion Criteria

  • Subjects are unable or unwilling to comply with the requirements of the study as determined by the investigator.
  • Investigator site personnel directly affiliated with this study and/or their immediate families; immediate family is defined as a spouse, parent, child, or sibling.
  • Cochlear employees or employees of Contract Research Organizations or contractors engaged by Cochlear for the purposes of this study.
  • For France only:
  • Subjects who are not affiliated to social security.
  • Subjects who are under legal protection.

Outcomes

Primary Outcomes

Number and Type of Contacts With Health Care Providers

Time Frame: From primary tympanoplasty to time of enrolment, up to 13 years

Contacts are obtained from medical records, counted and categorized.

Number and Type of Interventions and/or Procedures

Time Frame: From primary tympanoplasty to time of enrolment, up to 13 years

Medical examinations, surgical procedures and hearing rehabilitation are obtained from medical records, counted and categorized.

Number and Type of Medications and Therapies

Time Frame: From primary tympanoplasty to time of enrolment, up to 13 years

Medications are obtained from medical records, counted and categorized. Therapies from medical records are listed.

Secondary Outcomes

  • Hearing Performance Assessed Via an Audiogram(Up to 6 years prior to study enrollment)
  • Health Care Costs(From primary tympanoplasty to time of enrolment.)
  • Socio-economic Status and Health Care Data Via the Client Service Receipt Inventory (CSRI) Survey(At enrolment)
  • Self-reported Health Status and Health Related Quality of Life Via the Health Utilities Index Mark III (HUI3) Questionnaire.(At enrolment)
  • Self-reported Health Related Quality of Life of Participants With COM Via the Chronic Otitis Media Outcome Test-15 (COMOT-15) Questionnaire.(At enrolment)
  • Self-reported Auditory Disability Via the Speech, Spatial and Qualities of Hearing Scale (SSQ-12) Questionnaire(At enrolment)
  • Chronic Otitis Media Outcome Test -15 (COMOT-15) Questionnaire in German, French and Spanish(At enrollment)

Study Sites (6)

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